A Single-cell Transcriptome Atlas of the Mouse Glomerulus
Nikos Karaiskos1*, Mahdieh Rahmatollahi2*, Anastasiya Boltengagen1, Haiyue Liu1, Martin Hoehne2, Markus Rinschen2,3, Bernhard Schermer2,4,5, Thomas Benzing2,4,5, Nikolaus Rajewsky1, Christine Kocks1#, Martin Kann2*, Roman-Ulrich Müller2,4,5*#
1 Systems Biology of Gene Regulatory Elements, Berlin Institute for Medical Systems Biology (BIMSB), Max Delbrück Center for Molecular Medicine in the Helmholtz Association (MDC), 13125 Berlin, Germany.
2 Department II of Internal Medicine and Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.
3 Scripps Institute, San Diego, CA, USA
4 Cologne Excellence Cluster on Cellular Stress Responses in Aging-associated Diseases (CECAD), University of Cologne, Cologne, Germany.
5 Systems Biology of Ageing Cologne, University of Cologne, Cologne, Germany.
* These authors contributed equally to this work.
# To whom correspondence should be addressed: email@example.com, and firstname.lastname@example.org
The glomerulus single-cell atlas is created and maintained by Nikos Karaiskos.
The following features are currently supported in the atlas:
The raw (fastq files), as well as processed data (digital gene expression matrices for each replicate) is available at the GEO database under the accsession number GSE111107.
The final normalized, filtered gene expression matrices (after removing low quality cells and doublets) with cluster information can be downloaded directly for the full set of cells, the endothelial cells, or the podocytes.
Genome tracks for the major cell types from the pooled replicates are available here.